SS-31 (also called Elamipretide or Bendavia) is a mitochondria-targeted peptide. That means it was designed to work inside your mitochondria — the “power plants” of your cells.
Here’s what it does:
Targets mitochondria directly – Unlike most compounds, SS-31 can cross into mitochondria and bind to a lipid called cardiolipin, which is critical for mitochondrial structure and energy production.
Protects against oxidative stress – Mitochondria produce energy, but also generate harmful free radicals. SS-31 reduces oxidative stress and prevents damage to mitochondria.
Improves energy production – By stabilizing cardiolipin, SS-31 helps mitochondria make ATP (the body’s energy currency) more efficiently.
Reduces cell damage – It protects cells from apoptosis (programmed cell death) triggered by mitochondrial dysfunction.
Potential benefits being studied:
May improve heart function (studied in heart failure and ischemia).
Shows promise for kidney protection.
May help with age-related mitochondrial decline.
Investigated for muscle performance, neurodegeneration, and eye health (mitochondria are crucial in retinal cells).
In short:
SS-31 is like a shield + booster for your mitochondria. It helps them work better, produce more energy, and resist damage — which could translate into benefits for energy levels, aging, and organ protection.
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