SLU-PP-332

Description

What SLU-PP-332 Does (Mechanism of Action)

SLU-PP-332 is a pan-ERR agonist, meaning it activates:

• ERRα (Estrogen-Related Receptor alpha)

• ERRβ

• ERRγ

These receptors play a major role in:

• Mitochondrial function

• Oxidative metabolism

• Muscle endurance

• Fatty acid utilization

Unlike stimulants or hormones, SLU-PP-332 works at the gene-expression level, signaling cells to behave more like they do during endurance training.

Key Effects Observed in Research

🔋 Increased Mitochondrial Activity

• Promotes mitochondrial biogenesis

• Enhances ATP (energy) production

• Improves cellular “fuel efficiency”

🏃 Endurance-Like Adaptations (Without Exercise)

• Animal studies showed significant increases in endurance capacity

• Often described as an “exercise mimetic” in research literature

🔥 Shift Toward Fat Utilization

• Encourages fatty acid oxidation

• Reduces reliance on glucose for energy

• Metabolic profile similar to trained muscle tissue

🧬 Muscle Fiber Optimization

• Supports oxidative (slow-twitch–like) muscle characteristics

• Improves metabolic flexibility in skeletal muscle

What It Is Not

To keep expectations realistic:

• ❌ Not a stimulant

• ❌ Not a fat burner in the traditional sense

• ❌ Not anabolic or hormone-based

• ❌ Not approved for human use

All current data comes from preclinical and laboratory research.

Why Researchers Are Interested

SLU-PP-332 is being studied for potential insights into:

• Metabolic efficiency

• Muscle fatigue resistance

• Mitochondrial disorders

• Aging-related energy decline

Its ability to activate endurance pathways without physical training is what makes it particularly intriguing in research settings.