GDF-8

MYOSTATIN (GDF-8)

Myostatin (GDF-8) is a myokine, released by myocytes, it is a member of the TGF beta protein family. Myostatin (GDF-8) acts on muscle cells’ autocrine function to inhibit muscle cell growth and differentiation. In humans it is encoded by the MSTN gene, and the MSTN gene is located on the long (q) arm of chromosome 2 at position 32.2. Human Myostatin with total molecular weight is 25.0 kDa consists of 2 identical subunits, each consisting of 109 amino acid residues.